产品货号：
Z23303
中文名称：
PCSK9抗体
英文名称：
Anti-PCSK9 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-PCSK9 Antibody |
| 指标别名 | FH3;HCHOLA3;LDLCQ1;NARC 1;NARC1;PC9;PCSK9;Proprotein convertase 9 |
| 克隆性 | Polyclonal |
| 检验物种 | human |
| 应用范围 | WB,IHC,ELISA(Cap) |
| 基因名称 | PCSK9 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | E.coli-derived human PCSK9 recombinant protein (Position:S153-Q344). |
| 计算分子量 | 74KD |
| 实际分子量 | 62,78KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Proprotein convertase subtilisin/kexin type 9,also known as PCSK9,is an enzyme that in humans is encoded by the PCSK9 gene.This gene encodes a proprotein convertase belonging to the proteinase K subfamily of the secretory subtilase family.By genomic sequence analysis,PCSK9 was mapped to chromosome 1p32.This gene is a crucial player in the regulation of plasma cholesterol homeostasis.It may prevent the recycling of LDLR from endosomes to the cell surface or direct it to lysosomes for degradation.PCSK9 can induce ubiquitination of LDLR leading to its subsequent degradation.This gene is involved in the disposal of non-acetylated intermediates of BACE1 in the early secretory pathway. |
| Uniprot ID | Q8NBP7 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 推荐稀释比 | Western blot (WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:50～400 ELISA(Cap) 1:100～1000 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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